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Introduction to the Cellular and Molecular Biology of Cancer





Introduction to the Cellular and Molecular Biology of Cancer
List Price: $165.00
Our Price: $127.52
Your Save: $ 37.48 ( 23% )
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Manufacturer: Oxford University Press, USA

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Binding: Hardcover
Dewey Decimal Number: 616.994071
EAN: 9780198568537
ISBN: 0198568533
Label: Oxford University Press, USA
Manufacturer: Oxford University Press, USA
Number Of Items: 1
Number Of Pages: 552
Publication Date: 2005-09-15
Publisher: Oxford University Press, USA
Studio: Oxford University Press, USA

Editorial Reviews for Introduction to the Cellular and Molecular Biology of Cancer

This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.


Consumer reviews:

Customer Rating: Average rating of 5/5Average rating of 5/5Average rating of 5/5Average rating of 5/5Average rating of 5/5
Summary: A great primer for researchers
Comment: I'm a mathematics Ph.D. student who's working in computational oncology, meaning that I study cancer from a mathematical/engineering point of view (conservation of mass, oxygen and glucose transport, etc.) and create computer models for study. This biophysical viewpoint has been fruitful, but I've found that to make further progress, an understanding of the cellular biology is required. Furthermore, a lack of vocabulary makes it difficult to communicate with the clinical/medical community.

That's where this book comes in: it gives a great, expansive overview of cancer that is difficult to come by in the mathematical world. In places, it is perhaps too detail-oriented (which specific proteins do what and how, e.g., in DNA repair), but that's the nature of the beast, and I feel that it's very important for mathematical biologists to be exposed to this. The text gives a good sampling ranging from epidemiology, genetics and epigenetics (gene expression), oncogenes, tumor suppresor genes, DNA repair, cell cycle, and most approaches to therapy.

Because this edition was published in late 2005, it's quite up-to-date, and in that regard, the papers cited are very useful to the student and researcher for further exploration and paper writing. Probably one of the greater weaknesses is in the figures in the earlier genetics sections: the diagrams are not particularly helpful in actually illustrating the complex processes. Overall, though, this has been very helpful for me in bridging the gap between mathematical biology and oncology. I'd highly recommend this text for anybody who desires to learn more about the biology of the cancer, regardless of where they're coming from.


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Complete Record Information
Introduction to the cellular and molecular biology of cancer Franks, L. M. (Leonard Maurice). Edition : 2nd ed.


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