Chemistry of Peptide Synthesis
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List Price: $149.95
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Manufacturer: CRC
Written By: N. Leo Benoiton
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Binding: Hardcover
Dewey Decimal Number: 612.015756
EAN: 9781574444544
ISBN: 1574444549
Label: CRC
Manufacturer: CRC
Number Of Items: 1
Number Of Pages: 304
Publication Date: 2005-08-12
Publisher: CRC
Studio: CRC
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Editorial Reviews for Chemistry of Peptide Synthesis
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Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions. Incorporating elements from the author’s role of Career Investigator of the Medical Research Council of Canada and his extensive teaching career, the book emphasizes learning rather than memorization. The text uses clear language and schematics to present concepts progressively, carefully excluding unnecessary details and providing a historical context in which to appreciate the development of the field. The author first outlines the fundamentals of peptide synthesis, focusing on the intermediates in aminolysis reactions. Gradually the text builds into discussions of the applicability of coupling reactions, stereomutation, methods of deprotection, solid-phase synthesis, side-chain protection and side reactions, and amplification on coupling methods. The book clarifies the differences between oxazolones from amino-acid derivativesand segments and the implications of their formation on the chiral integrity of products. The author offers a critical analysis of the mechanisms of coupling reactions and the desirability of preactivation. The text explains hindrance and the nucleophilicity of tertiary amines and rationalizes their use. The book also explores mechanisms of acidolysis and the dual role of nucleophiles as reactants and scavengers. Chemistry of Peptide Synthesis supplies a broad, yet straightforward approach that appeals to those with limited knowledge of organic chemistry or chemists from other fields as well as in-depth coverage that can be appreciated by experienced peptidologists.
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More Information on Chemistry of Peptide Synthesis
Review: Chemistry of Peptide Synthesis
his useful but expensive CRC Press book describes the chemical reactions for chemically synthesizing peptides, a topic that is constantly changing due to the enormous economic ...
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Chemistry of Peptide Synthesis: N. Leo Benoiton: Read it Online! Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to ...
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... while being invaluable to the less experienced. Pat Bailey in the Times Higher Education Supplement ' - 'This is a good, plain, traditional book on the chemistry of peptide synthesis ...
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Chemistry of Peptide Synthesis: N. Leo Benoiton: Read it Online! Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to ...
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Chemistry of Peptide Synthesis is a complete overview of how peptides are synthesized and what techniques are likely to generate the most desirable reactions.
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... they are both based on fundamentally same principles: one is a solution method and the other being a solid-phase method carried out on a resin. The chemistry of peptide synthesis was ...
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